US scientists put nanomotors into human cells to diagnose and treat diseases

Release date: 2014-02-21

For the first time, researchers at Pennsylvania State University placed nanomotors in living human cells and manipulated them by magnetic force. This technological advancement will drive the use of molecular machines, such as releasing drugs to specific locations within the body. The research results are published in the latest issue of the International Edition of Applied Chemistry. Until now, nanomotors have been limited to in vitro and in laboratory settings and have not been used in living human cells. Professor Tom, a materials scientist at the university, said: "These nanomotors surround the cells and crash into the structure of the cells, showing the mechanical reaction inside the living cells, which no one has seen before. It's a lively demonstration, it may be a new way to study cell biology using synthetic nanomotors.” This method uses ultrasonic pulses to propel rocket-like metal particles, which enhances the drug's effectiveness while minimizing side effects. . At low ultrasound power, the nanomotor has little effect on these cells. However, as the power supply increases, the nanomotor squeaks out, zooms and slams into the organelle to perform a specific function within the cellular structure. Nanomotors can be thought of as "egggers" that essentially homogenize the contents of the cells or pierce the cell membrane as a stick. Tom said: "We may be able to use nanomotors to manipulate cells from inside to treat cancer and other diseases. It can also be used for intracellular surgery and non-invasive delivery of drugs into living tissue." Researchers have been able to use magnetic control. This tiny motor. They also found that the nanomotors can move autonomously and independently of one another, an ability that is important for future applications. Tom explained: "Autonomous exercise may help the nanomotor to selectively search for cancer cells and kill them. Therefore, if you want these motors to find and destroy cancer cells, it is best to let them move independently, not one. The big group walked in one direction.” In describing the potential use of nanomotor technology, the researchers cited a scene from a 1966 science fiction film in which a submarine and crew were miniaturized in order to inject into a dying person. To save his life in the blood. Tom explained that one of the dreams of our application is that nanomotors will swim in the human body, communicate with drugs, and carry out various kinds of diagnosis and treatment. Imagine that you can put a mechanical surgical scalpel into a blood vessel. It goes into a heart diagnostic view. When one of the valves is found to be one of the faults, it is cut off with a knife.


Source: China Science and Technology Network - Technology Daily

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