The five pillars of the treatment of cancer
Release date: 2015-04-29
Surgery, chemotherapy, radiation therapy, targeted therapy, and immunotherapy are the five pillars of today's cancer treatment.
The tumor in the mind of the average person is a cell that grows out of control, and there seems to be no other bad behavior except for super-life. Learn more about the fact that tumor cells are variant cells, although they are born in tissues but do not have many normal cellular functions. It is equivalent to the hooligans. In fact, cancer is not just a street gangster, but rather a tightly organized underworld. Tumor tissue not only has the advantage of growth, resists the signal of apoptosis, but also establishes its own nutrient supply system, bribery public inspection (immune system), and becomes an independent kingdom above the law. Tumor cells can release a variety of signals to the body, organized and planned to spread to other tissues. It is this ability to spread that leads to the patient's last death. It is almost impossible to believe that such a complex evil institution was created by a random variation of cells. It should be that the complex normal tissue differentiation system of the human body plays a role in fueling and even decisive under the wrong signal.
Surgery is the easiest strategy to understand, and it is equivalent to destroying the underworld with its neighbors. As long as this underworld organization does not penetrate very widely, this is the best way. Until recently, surgery was the only cure for many tumors. But if the tumor has spread a lot, you have to use other treatments.
Both chemotherapy and radiotherapy target cells that differentiate faster. This is like hearing that the members of the underworld are active in nightlife, so they are all shot on the streets after 9 pm. Although this can indeed kill a lot of tumor cells, but there are too many people who have been injured. In addition, there are always a lot of tumor cells that will survive (the current detection limit is 1 billion cells), and according to Darwin's theory, it is those who are the most sinful. When they come back, they only use other treatments because these guys have been resistant to the chemotherapy and radiotherapy used.
Targeted therapy is like arresting black bosses. This method is more selective than the violent methods such as chemotherapy and radiotherapy, and the side effects are small. However, the underworld is not a problem for the black boss. If this head is not in the future, the next big brother will be elected soon. The Gen Xian Incident cannot solve the conflict between the Kuomintang and the Communist Party. Therefore, although targeted therapy can have a very thorough response, it has poor persistence. Most kinase inhibitors can only temporarily shrink tumors below the detection limit, tumors recur very quickly, and few targeted drugs can really extend the life of patients.
Immunotherapy for cancer has shown great power in recent years. After all, tumor cells are different from normal cells, and the body's immune system can be said to be able to recognize tumor cells. However, the tumor is flawed in that it can release various immune suppression signals, which is equivalent to the underworld bribery public inspection method. In fact, there are a large number of immune cells in the vicinity of many tumor tissues, that is, the immune system is ready to fight these criminals, but there is always a protective umbrella to prevent blackouts. At present, the checkpoint inhibitors represented by PD-1 inhibitors have removed these umbrellas, and the black forces represented by melanoma have been severely hit. For the hidden underworld, CAR-T, TCR and other technologies can train a large number of police officers who can find these black-related personnel, and also show good results.
For now, if I compare these five pillars, I think the most promising immunotherapy. Although it may be necessary to use these technologies in combination to maximize the control of tumors, it is more effective than any other method to eliminate the umbrella according to our experience in sweeping yellow and black. Similarly, immunotherapy and tumors are the most complex and most likely to be at the heart of future cancer treatments.
Source: US and Chinese medicine source
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