Pharmaceutical Material CAS184475-35-2 Gefitinib as Tyrosine Kinase Inhibitor

Model NO.: Gefitinib
CAS: 184475-35-2
Delivery Time: Within 3-5 Days After Payment
Certificates: ISO9001
Grade: Pharmaceutical Grade
Express Way: EMS, FedEx, TNT, DHL, Hkems
Export Market: Global
Trademark: JCJ
Transport Package: Customized
Specification: usp
Origin: China
HS Code: 456789
Model NO.: Gefitinib
CAS: 184475-35-2
Delivery Time: Within 3-5 Days After Payment
Certificates: ISO9001
Grade: Pharmaceutical Grade
Express Way: EMS, FedEx, TNT, DHL, Hkems
Export Market: Global
Trademark: JCJ
Transport Package: Customized
Specification: usp
Origin: China
HS Code: 456789
CAS184475-35-2 Gefitinib as Tyrosine kinase inhibitor

Gefitinib Basic information

Product Name:    Gefitinib
Synonyms:    N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Gefitinib;Gefitinib, >=99%;N-(3-Chlor-4-fluorophenyl)-7-[methoxy-6-[(3-morpholin-4-yl)propoxyl]-quinazolin-4-yl]amine;GEFITINIB RELATED COMPOUND;Gefitinib(TINIBS);6-(Benzyloxy)-7-methoxyquinazolin-4(3H)-one;Gefinitib;(3-chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl]amine
CAS:    184475-35-2
MF:    C22H24ClFN4O3
MW:    446.9
EINECS:    1308068-626-2


Gefitinib COA 

 
Product name Gefitinib
CAS
CAS No.

184475-35-2

Outer Packing


19.7kg

Production date

Mar. 03.2017

Shelf life

Mar. 02.2019

Standard adopted


Enterprise standard

Items of analysis

Specification

Results


Appearance


White to almost white crystalline powder.


Conform


Identification


FT-IR,HPLC


Conform


Melting


193ºC~197ºC


194.2ºC~196.1ºC


Water


≤1.0%


0.47%


Heavy metals


≤20 ppm


<20 ppm


Residual solution


≤0.1%


0.06%


N,N-Dimethylformamide


<=880ppm


N.D


Methanol


<=3000ppm


350ppm


Dichloromethane


<=600ppm


N.D


Ethanol


<=5000ppm


N.D


Acetone


<=5000ppm


N.D


Maximum individual Impurity


≤0.10%


0.04%


Total impurities


≤0.4%


0.15%


Purity


≥99.6%


99.85%


Assay


98.0%~102.0%


99.5%

Conclusion

Qualified


Deferred products: Gefitinib tablets

Gefitinib Use: First-line treatment of locally advanced or metastatic non-small cell carcinoma (NSCLC) patients

with sensitive mutations in the epidermal growth factor receptor (EGFR) gene and locally advanced or

metastatic non-small cell carcinomas that have been treated with chemotherapy ( NSCLC)

Gefitinib Usage and dosage: Recommended dose is 250mg (1 tablet) once daily, fasting or with food. Not

recommended for children or adolescents, the safety and efficacy of this patient population have not been

studied. If there is difficulty in swallowing, the tablet can be dispersed in half a cup of drinking water (non-carbonated beverages) and no other liquids can be used. Discard the tablets in water without crushing, stir until

completely dispersed (approximately 10 minutes) and drink immediately. Rinse the cup with half a glass of water

and drink. The drug solution can also be administered through a nasal-stomach tube. There is no need to

adjust doses due to different conditions: age, weight, sex, race, kidney function, moderate to severe liver

damage due to liver metastases. Dose adjustment: When the patient has intolerable diarrhea or adverse skin

reactions, it can be resolved by short-term treatment (up to 14 days), followed by a daily dose of 250 mg.



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3.best free resend  policy .
4.professional warehouse and reliable express agent with disguise package .
5.over 98% passing rate .
6.top quality is our life .
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  CAS184475-35-2 Gefitinib as Tyrosine kinase inhibitor

Gefitinib Basic information

Product Name:    Gefitinib
Synonyms:    N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Gefitinib;Gefitinib, >=99%;N-(3-Chlor-4-fluorophenyl)-7-[methoxy-6-[(3-morpholin-4-yl)propoxyl]-quinazolin-4-yl]amine;GEFITINIB RELATED COMPOUND;Gefitinib(TINIBS);6-(Benzyloxy)-7-methoxyquinazolin-4(3H)-one;Gefinitib;(3-chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl]amine
CAS:    184475-35-2
MF:    C22H24ClFN4O3
MW:    446.9
EINECS:    1308068-626-2


Gefitinib COA 

 
Product name Gefitinib
CAS
CAS No.

184475-35-2

Outer Packing


19.7kg

Production date

Mar. 03.2017

Shelf life

Mar. 02.2019

Standard adopted


Enterprise standard

Items of analysis

Specification

Results


Appearance


White to almost white crystalline powder.


Conform


Identification


FT-IR,HPLC


Conform


Melting


193ºC~197ºC


194.2ºC~196.1ºC


Water


≤1.0%


0.47%


Heavy metals


≤20 ppm


<20 ppm


Residual solution


≤0.1%


0.06%


N,N-Dimethylformamide


<=880ppm


N.D


Methanol


<=3000ppm


350ppm


Dichloromethane


<=600ppm


N.D


Ethanol


<=5000ppm


N.D


Acetone


<=5000ppm


N.D


Maximum individual Impurity


≤0.10%


0.04%


Total impurities


≤0.4%


0.15%


Purity


≥99.6%


99.85%


Assay


98.0%~102.0%


99.5%

Conclusion

Qualified


Deferred products: Gefitinib tablets

Gefitinib Use: First-line treatment of locally advanced or metastatic non-small cell carcinoma (NSCLC) patients

with sensitive mutations in the epidermal growth factor receptor (EGFR) gene and locally advanced or

metastatic non-small cell carcinomas that have been treated with chemotherapy ( NSCLC)

Gefitinib Usage and dosage: Recommended dose is 250mg (1 tablet) once daily, fasting or with food. Not

recommended for children or adolescents, the safety and efficacy of this patient population have not been

studied. If there is difficulty in swallowing, the tablet can be dispersed in half a cup of drinking water (non-carbonated beverages) and no other liquids can be used. Discard the tablets in water without crushing, stir until

completely dispersed (approximately 10 minutes) and drink immediately. Rinse the cup with half a glass of water

and drink. The drug solution can also be administered through a nasal-stomach tube. There is no need to

adjust doses due to different conditions: age, weight, sex, race, kidney function, moderate to severe liver

damage due to liver metastases. Dose adjustment: When the patient has intolerable diarrhea or adverse skin

reactions, it can be resolved by short-term treatment (up to 14 days), followed by a daily dose of 250 mg.



About Us:
 
1.8hour deliver after payment .
2.20% lower price that the market price .
3.best free resend  policy .
4.professional warehouse and reliable express agent with disguise package .
5.over 98% passing rate .
6.top quality is our life .
7.24h after-sales service.
8.more discount plz connect me ,,a gift is waiting for you .
Other steroid products:




Advantage : More than 11,000 material in stock . Any inquiry on pharmaceutical ,chemical etc, we can supply one time . Gurantee shipping within 3 hours ,promise 5-7 business days on delivery 

If you are need safe and fast way , we will be your best choice .Do not hesitate to contact us if you need :)

24 hours service online 

Contact Yolanda :)
 

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