Pharmaceutical Material CAS184475-35-2 Gefitinib as Tyrosine Kinase Inhibitor
Model NO.: Gefitinib
CAS: 184475-35-2
Delivery Time: Within 3-5 Days After Payment
Certificates: ISO9001
Grade: Pharmaceutical Grade
Express Way: EMS, FedEx, TNT, DHL, Hkems
Export Market: Global
Trademark: JCJ
Transport Package: Customized
Specification: usp
Origin: China
HS Code: 456789
Model NO.: Gefitinib
CAS: 184475-35-2
Delivery Time: Within 3-5 Days After Payment
Certificates: ISO9001
Grade: Pharmaceutical Grade
Express Way: EMS, FedEx, TNT, DHL, Hkems
Export Market: Global
Trademark: JCJ
Transport Package: Customized
Specification: usp
Origin: China
HS Code: 456789
CAS184475-35-2 Gefitinib as Tyrosine kinase inhibitorGefitinib Basic information
Product Name:Â Â Â Gefitinib
Synonyms:Â Â Â N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Gefitinib;Gefitinib, >=99%;N-(3-Chlor-4-fluorophenyl)-7-[methoxy-6-[(3-morpholin-4-yl)propoxyl]-quinazolin-4-yl]amine;GEFITINIB RELATED COMPOUND;Gefitinib(TINIBS);6-(Benzyloxy)-7-methoxyquinazolin-4(3H)-one;Gefinitib;(3-chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl]amine
CAS:Â Â Â 184475-35-2
MF:Â Â Â C22H24ClFN4O3
MW:Â Â Â 446.9
EINECS:Â Â Â 1308068-626-2
Gefitinib COAÂ
Â
Product name | Gefitinib | |||
CAS CAS No. |
184475-35-2 |
Outer Packing |
19.7kg |
|
Production date |
Mar. 03.2017 |
Shelf life |
Mar. 02.2019 |
|
Standard adopted |
Enterprise standard |
|||
Items of analysis |
Specification |
Results |
||
Appearance |
White to almost white crystalline powder. |
Conform |
||
Identification |
FT-IR,HPLC |
Conform |
||
Melting |
193ºC~197ºC |
194.2ºC~196.1ºC |
||
Water |
≤1.0% |
0.47% |
||
Heavy metals |
≤20 ppm |
<20 ppm |
||
Residual solution |
≤0.1% |
0.06% |
||
N,N-Dimethylformamide |
<=880ppm |
N.D |
||
Methanol |
<=3000ppm |
350ppm |
||
Dichloromethane |
<=600ppm |
N.D |
||
Ethanol |
<=5000ppm |
N.D |
||
Acetone |
<=5000ppm |
N.D |
||
Maximum individual Impurity |
≤0.10% |
0.04% |
||
Total impurities |
≤0.4% |
0.15% |
||
Purity |
≥99.6% |
99.85% |
||
Assay |
98.0%~102.0% |
99.5% |
||
Conclusion |
Qualified |
Deferred products: Gefitinib tablets
Gefitinib Use: First-line treatment of locally advanced or metastatic non-small cell carcinoma (NSCLC) patients
with sensitive mutations in the epidermal growth factor receptor (EGFR) gene and locally advanced or
metastatic non-small cell carcinomas that have been treated with chemotherapy ( NSCLC)
Gefitinib Usage and dosage: Recommended dose is 250mg (1 tablet) once daily, fasting or with food. Not
recommended for children or adolescents, the safety and efficacy of this patient population have not been
studied. If there is difficulty in swallowing, the tablet can be dispersed in half a cup of drinking water (non-carbonated beverages) and no other liquids can be used. Discard the tablets in water without crushing, stir until
completely dispersed (approximately 10 minutes) and drink immediately. Rinse the cup with half a glass of water
and drink. The drug solution can also be administered through a nasal-stomach tube. There is no need to
adjust doses due to different conditions: age, weight, sex, race, kidney function, moderate to severe liver
damage due to liver metastases. Dose adjustment: When the patient has intolerable diarrhea or adverse skin
reactions, it can be resolved by short-term treatment (up to 14 days), followed by a daily dose of 250 mg.
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2.20% lower price that the market price .
3.best free resend  policy .
4.professional warehouse and reliable express agent with disguise package .
5.over 98% passing rate .
6.top quality is our life .
7.24h after-sales service.
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 CAS184475-35-2 Gefitinib as Tyrosine kinase inhibitor
Gefitinib Basic information
Product Name:Â Â Â Gefitinib
Synonyms:Â Â Â N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Gefitinib;Gefitinib, >=99%;N-(3-Chlor-4-fluorophenyl)-7-[methoxy-6-[(3-morpholin-4-yl)propoxyl]-quinazolin-4-yl]amine;GEFITINIB RELATED COMPOUND;Gefitinib(TINIBS);6-(Benzyloxy)-7-methoxyquinazolin-4(3H)-one;Gefinitib;(3-chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl]amine
CAS:Â Â Â 184475-35-2
MF:Â Â Â C22H24ClFN4O3
MW:Â Â Â 446.9
EINECS:Â Â Â 1308068-626-2
Gefitinib COAÂ
Â
Product name | Gefitinib | |||
CAS CAS No. |
184475-35-2 |
Outer Packing |
19.7kg |
|
Production date |
Mar. 03.2017 |
Shelf life |
Mar. 02.2019 |
|
Standard adopted |
Enterprise standard |
|||
Items of analysis |
Specification |
Results |
||
Appearance |
White to almost white crystalline powder. |
Conform |
||
Identification |
FT-IR,HPLC |
Conform |
||
Melting |
193ºC~197ºC |
194.2ºC~196.1ºC |
||
Water |
≤1.0% |
0.47% |
||
Heavy metals |
≤20 ppm |
<20 ppm |
||
Residual solution |
≤0.1% |
0.06% |
||
N,N-Dimethylformamide |
<=880ppm |
N.D |
||
Methanol |
<=3000ppm |
350ppm |
||
Dichloromethane |
<=600ppm |
N.D |
||
Ethanol |
<=5000ppm |
N.D |
||
Acetone |
<=5000ppm |
N.D |
||
Maximum individual Impurity |
≤0.10% |
0.04% |
||
Total impurities |
≤0.4% |
0.15% |
||
Purity |
≥99.6% |
99.85% |
||
Assay |
98.0%~102.0% |
99.5% |
||
Conclusion |
Qualified |
Deferred products: Gefitinib tablets
Gefitinib Use: First-line treatment of locally advanced or metastatic non-small cell carcinoma (NSCLC) patients
with sensitive mutations in the epidermal growth factor receptor (EGFR) gene and locally advanced or
metastatic non-small cell carcinomas that have been treated with chemotherapy ( NSCLC)
Gefitinib Usage and dosage: Recommended dose is 250mg (1 tablet) once daily, fasting or with food. Not
recommended for children or adolescents, the safety and efficacy of this patient population have not been
studied. If there is difficulty in swallowing, the tablet can be dispersed in half a cup of drinking water (non-carbonated beverages) and no other liquids can be used. Discard the tablets in water without crushing, stir until
completely dispersed (approximately 10 minutes) and drink immediately. Rinse the cup with half a glass of water
and drink. The drug solution can also be administered through a nasal-stomach tube. There is no need to
adjust doses due to different conditions: age, weight, sex, race, kidney function, moderate to severe liver
damage due to liver metastases. Dose adjustment: When the patient has intolerable diarrhea or adverse skin
reactions, it can be resolved by short-term treatment (up to 14 days), followed by a daily dose of 250 mg.
About Us:
Â
1.8hour deliver after payment .
2.20% lower price that the market price .
3.best free resend  policy .
4.professional warehouse and reliable express agent with disguise package .
5.over 98% passing rate .
6.top quality is our life .
7.24h after-sales service.
8.more discount plz connect me ,,a gift is waiting for you .
Other steroid products:
Advantage : More than 11,000 material in stock . Any inquiry on pharmaceutical ,chemical etc, we can supply one time . Gurantee shipping within 3 hours ,promise 5-7 business days on deliveryÂ
If you are need safe and fast way , we will be your best choice .Do not hesitate to contact us if you need :)
24 hours service onlineÂ
Contact Yolanda :)
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