New interference imaging method for medical diagnosis
Release date: 2007-02-08
New interference imaging method for medical diagnosis
Scientists at the University of Illinois at Urbana-Champaign have recently invented a new computational imaging technique that uses the original fuzzy out-of-focus data to obtain new three-dimensional images. This technique is called Interferometric Synthetic Aperture Microscopy (ISAM), which combines the advantages of nuclear magnetic resonance technology with X-ray imaging interrupted-layer chromatography to improve the image quality of optical microscopy. Stephen Boppart, a professor of bioengineering, said: "ISAM enables high-speed, micron-level imaging without the time-consuming processing of the organization." The results of the group have been accepted by Nature Physics and published on the website. The technology was developed by post-doctoral Tyler Ralston, scientist Daniel Marks, and computer engineering professor P. Scott Carney. It utilizes a wide-spectrum light source and an interferometer to acquire high-resolution images reconstructed from the optical signals of the sample. "ISAM has great potential in real-time 3D imaging and can be used in cell and tumor biology," Boppart said. "This technique is more suitable for clinical diagnosis than biopsies." Existing 3D optical microscopy requirements The focal plane of the device scans the region of interest for the sample, while the ISAM utilizes light that is focused outside of the imaging plane. Ralston said: "Although most areas of the imaging plane are blurred, ISAM can use this light to get a fully focused 3D image." ISAM uses data that was discarded in the past to expand the imageable area. Mark said: "We have demonstrated that the use of discarded data can be reconstructed computationally to get the image we need. The team is currently applying this technology to microscopic imaging techniques for a variety of organisms." This powerful technology only needs Small modifications can be used on existing hardware. —— Information from: Meditech Medical Network
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