Pharmaceutical Raw Powder Gefixtinib for Breast Cancer Treating
Pharmaceutical Raw Powder  Gefixtinib for Breast Cancer Treating
Description
Gefi xtinib is the first selective inhibitor of epidermal growth  receptor's (EGFR) tyrosine kinase domain. Thus Gefi xtinib is an EGFR inhibitor. The target protein (EGFR) is a family of receptors which includes Her1(erb-B1), Her2(erb-B2 ), and Her 3(erb-B3). EGFR is overexpressed in the cells of certain types of human carcinomas - for example in lung and breast cancers.
COA
Tests |
Specification |
Results |
Appearance |
Slight white to white crystalline powder |
White crystalline powder |
Identification IR(1) |
Conforms to the refence |
Conforms to the refence |
Melting Point |
194.0~198.0°C |
196.0~197.0°C |
Water(KF) |
≤0.30% |
0.05% |
Assay (HPLC) |
≥99.0% |
99.9% |
Individual Purity (HPLC ) |
≤0.20% |
0.09% |
Conclusion |
Conform with company standard  |
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How does it work?
Research on Gefi xtinib-sensitive non-small cell lung cancers has shown that a mutation in the EGFR tyrosine kinase domain is responsible for activating anti-apoptotic Pathways.
These mutations tend to confer increased sensitivity to tyrosine kinase inhibitors such as Gefi xtinib and erlotinib. Of the types of non-small cell lung cancer histologies, adenocarcinoma is the type that most often harbors these mutations. These mutations are more commonly seen in Asians, women , and non-smokers (who also tend to more often have adenocarcinoma).
Gefi xtinib inhibits EGFR tyrosine kinase by binding to the adenosine triphosphate (ATP)-binding site of the enzyme. Thus the function of the EGFR tyrosine kinase in activating the anti-apoptotic Ras signal transduction cascade is inhibited, and malignant cells are inhibited.
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How to use Gefi xtinib Tablet
Take Gefi xtinib by mouth once daily, with or without food, or as directed.
Medications which reduce or completely block stomach acid (e.g., proton pump inhibitors/PPIs, H2 blockers, antacids) may decrease the absorption of Gefi xtinib. This could decrease the effectiveness of Gefi xtinib. Consult your doctor or pharmacist if you are taking any of these medications.
Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day.
Other Detail
Payment terms | Western union , Money gram, Bank transfer |
Min order quantity | 10vail |
Delivery | Sent out within 48 hours after payment confirmed |
Lead time | 4-7 days |
Packaging | Disguised package or as required |
Origin | China |
Shipping | Express Courier(EMS,DHL,UPS,TNT,ect) |
Discount | Multiple items ordered one time |
Larger quantity of each item |
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FAQ
What about the payment?Is it secure?
A:Payment can be TT, West Union, Money Gram and Bitcoin. As a well-known supplier, thousands of buyers pay as mentioned. It is warmly welcome to visit our company, discuss and deal face to face.
Have your product quality been approved by Third Party Lab?
A:Yes,All products are strictly tested by our QC,confirmed by QA and approved by third party lab in China,USA,Canada,Germany,UK,Italy,France etc.So you will be assured with Good Quality if you choose us.
Do you accept sample order?
A:Yes,we accept small order from 10g,100g and 1kg for your evaluation quality of our goods.
Is there any discount?
A:Yes,for larger quantity,we always support with better price.
Do you have any reshipment policy?
A:Yes we will reship for totally free if your parcles is seizd by customs unlucky,you dont need to pay any more money
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Any other questions,please freely contact me .
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Pharmaceutical Raw Powder  Gefixtinib for Breast Cancer Treating
Description
Gefi xtinib is the first selective inhibitor of epidermal growth  receptor's (EGFR) tyrosine kinase domain. Thus Gefi xtinib is an EGFR inhibitor. The target protein (EGFR) is a family of receptors which includes Her1(erb-B1), Her2(erb-B2 ), and Her 3(erb-B3). EGFR is overexpressed in the cells of certain types of human carcinomas - for example in lung and breast cancers.
COA
Tests |
Specification |
Results |
Appearance |
Slight white to white crystalline powder |
White crystalline powder |
Identification IR(1) |
Conforms to the refence |
Conforms to the refence |
Melting Point |
194.0~198.0°C |
196.0~197.0°C |
Water(KF) |
≤0.30% |
0.05% |
Assay (HPLC) |
≥99.0% |
99.9% |
Individual Purity (HPLC ) |
≤0.20% |
0.09% |
Conclusion |
Conform with company standard  |
Â
How does it work?
Research on Gefi xtinib-sensitive non-small cell lung cancers has shown that a mutation in the EGFR tyrosine kinase domain is responsible for activating anti-apoptotic Pathways.
These mutations tend to confer increased sensitivity to tyrosine kinase inhibitors such as Gefi xtinib and erlotinib. Of the types of non-small cell lung cancer histologies, adenocarcinoma is the type that most often harbors these mutations. These mutations are more commonly seen in Asians, women , and non-smokers (who also tend to more often have adenocarcinoma).
Gefi xtinib inhibits EGFR tyrosine kinase by binding to the adenosine triphosphate (ATP)-binding site of the enzyme. Thus the function of the EGFR tyrosine kinase in activating the anti-apoptotic Ras signal transduction cascade is inhibited, and malignant cells are inhibited.
Â
How to use Gefi xtinib Tablet
Take Gefi xtinib by mouth once daily, with or without food, or as directed.
Medications which reduce or completely block stomach acid (e.g., proton pump inhibitors/PPIs, H2 blockers, antacids) may decrease the absorption of Gefi xtinib. This could decrease the effectiveness of Gefi xtinib. Consult your doctor or pharmacist if you are taking any of these medications.
Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day.
Other Detail
Payment terms | Western union , Money gram, Bank transfer |
Min order quantity | 10vail |
Delivery | Sent out within 48 hours after payment confirmed |
Lead time | 4-7 days |
Packaging | Disguised package or as required |
Origin | China |
Shipping | Express Courier(EMS,DHL,UPS,TNT,ect) |
Discount | Multiple items ordered one time |
Larger quantity of each item |
Hot Products
Dehydronandrolon | CAS:2590-41-2 |
Flugestone Acetate | CAS:2529-45-5 |
Methyldienedione | CAS:5173-46-6 |
17-Hydroxy Progesterone | CAS:68-96-2Â Â |
Altrenogest | CAS:850-52-2 |
Pregnenolone | CAS:145-13-1 |
Megestrol Acetate | CAS:595-33-5 |
Cyproterone Acetate | CAS:427-51-0 |
Medroxyprogesterone 17-Acetate | CAS:71-58-9 |
Levonorgestrel | CAS:797-63-7 |
Diethylstilbestrol | CAS:56-53-1 |
Estradiol Valerate | CAS:979-32-8 |
Estriol | CAS:50-27-1 |
Estradiol Benzoate | CAS:50-50-0 |
Esterone | CAS:53-16-7 |
Ethynyl Estradiol | CAS:57-63-6 |
Mifepristone | CAS:84371-65-3 |
Dienogestrel | CAS:65928-58-7 |
Misoprostol | CAS:59122-46-2 |
6-bromoandrostenedione | CAS:38632-00-7 |
Cabergoline | CAS:81409-90-7Â Â Â |
Methoxydienone | CAS:2322-77-2 |
Diflorasone | CAS:2557-49-5 |
FAQ
What about the payment?Is it secure?
A:Payment can be TT, West Union, Money Gram and Bitcoin. As a well-known supplier, thousands of buyers pay as mentioned. It is warmly welcome to visit our company, discuss and deal face to face.
Have your product quality been approved by Third Party Lab?
A:Yes,All products are strictly tested by our QC,confirmed by QA and approved by third party lab in China,USA,Canada,Germany,UK,Italy,France etc.So you will be assured with Good Quality if you choose us.
Do you accept sample order?
A:Yes,we accept small order from 10g,100g and 1kg for your evaluation quality of our goods.
Is there any discount?
A:Yes,for larger quantity,we always support with better price.
Do you have any reshipment policy?
A:Yes we will reship for totally free if your parcles is seizd by customs unlucky,you dont need to pay any more money
Â
Any other questions,please freely contact me .
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