99.6% High Purity Lapatinib Ditosylate (CAS 388082-78-8)
Model NO.: 388082-78-8
Delivery Time: Shipped in 3 Days After Payment
Payment Method: T/T, Western Union, Money Gram, Paypal
Shipping Method: EMS, DHL, FedEx, etc(Door-to-Door)
Usage: Treating Cancer
Appearence: off-White Solid
Mf: C41h40clfn4o11s3
Quality Standard: Bp, USP, Ep, Cp
Trademark: Disel
Transport Package: Foil Bag, Drum or Carton
Origin: Hubei
Model NO.: 388082-78-8
Delivery Time: Shipped in 3 Days After Payment
Payment Method: T/T, Western Union, Money Gram, Paypal
Shipping Method: EMS, DHL, FedEx, etc(Door-to-Door)
Usage: Treating Cancer
Appearence: off-White Solid
Mf: C41h40clfn4o11s3
Quality Standard: Bp, USP, Ep, Cp
Trademark: Disel
Transport Package: Foil Bag, Drum or Carton
Origin: Hubei
Quick Details:
Product Name: Lapatinib ditosylate
Synonyms: Â Lapatinib ditosylate;benzenesulfonic acid: N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6 -[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine: h ydrate;N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine bis(4-methylbenzenesulfonate);Lapatinib Ditosilate;Lapatinib, Tykerb, GW572016;Lapatinib Ditosylate (GW-572016);lapatinib(GW572016);Lapatinib ditosylate hydrate
CAS: 388082-78-8
MF: Â C41H40ClFN4O11S3
MW: Â 925.46
Product Categories: anti-neoplastic;Lapatinib;Anti-cancer&immunity;Inhibitors
Mol File: Â 388082-78-8.mol
COA:
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TEST ITEMS | SPECIFICATION | RESULTS |
Description | Light yellow or almost white crystalline powder | Light  Yellow powder |
Identification | IR | Positive |
Assay | 97.0~103.0% | 99.37% |
Melting Point | 70~80°C | 70.5~76.5°C |
Specific Rotation | +22~+26° | +23.09° |
Loss On Drying | 0.5%max | 0.25% |
Residue On Ignition | 0.1%max | 0.05% |
Heavy Metals | 20PPm max | <20PPm |
Organic Volatile Impurities | Meets the requirement. | Conforms |
Related Substances |
Single Impurity: 1.0%max | <1.0% |
Total Impurities: 2.0%max | <2.0% | |
Conclusion | The specification conforms to enterprise standard. |
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Breast Cancer:
In combination with letrozole for treatment of hormone receptor-positive metastatic breast cancer that overexpresses the human epidermal receptor type 2 (HER2) protein in postmenopausal women who are candidates for hormonal therapy.1Â 5Â 8Â Combined therapy with lapatinib and an aromatase inhibitor has not been compared with trastuzumab-containing chemotherapy for treatment of metastatic breast cancer.
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Quick Details:
Product Name: Lapatinib ditosylate
Synonyms: Â Lapatinib ditosylate;benzenesulfonic acid: N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6 -[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine: h ydrate;N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine bis(4-methylbenzenesulfonate);Lapatinib Ditosilate;Lapatinib, Tykerb, GW572016;Lapatinib Ditosylate (GW-572016);lapatinib(GW572016);Lapatinib ditosylate hydrate
CAS: 388082-78-8
MF: Â C41H40ClFN4O11S3
MW: Â 925.46
Product Categories: anti-neoplastic;Lapatinib;Anti-cancer&immunity;Inhibitors
Mol File: Â 388082-78-8.mol
COA:
Â
TEST ITEMS | SPECIFICATION | RESULTS |
Description | Light yellow or almost white crystalline powder | Light  Yellow powder |
Identification | IR | Positive |
Assay | 97.0~103.0% | 99.37% |
Melting Point | 70~80°C | 70.5~76.5°C |
Specific Rotation | +22~+26° | +23.09° |
Loss On Drying | 0.5%max | 0.25% |
Residue On Ignition | 0.1%max | 0.05% |
Heavy Metals | 20PPm max | <20PPm |
Organic Volatile Impurities | Meets the requirement. | Conforms |
Related Substances |
Single Impurity: 1.0%max | <1.0% |
Total Impurities: 2.0%max | <2.0% | |
Conclusion | The specification conforms to enterprise standard. |