Embryonic stem cell cloning success raises concerns
Release date: 2013-05-20
The prospect of tailoring my future baby according to my wishes has become clearer: a recent study on embryo cloning has resulted in the extraction of human stem cells from cloned human embryos, a human egg cell that is preparing to remove the nucleus, which is relevant. The first step of the operation is to culture human embryos and try to extract stem cells when they grow to five or six days, but this study also raises a wide range of ethical concerns that the future can be ensured by stem cells by extracting a small amount on the patient's skin. Alternatives to technical production are fully matched to the patient. This will greatly enhance the effectiveness of treatment and prevent the body's immune rejection. May 17th, Beijing time, according to the British "Daily Mail" report, we are one step further from the clone. Scientists have recently successfully extracted stem cells from laboratory-cultured human embryos. This is an important development. This breakthrough is expected to allow scientists to use stem cell technology to treat a range of difficult diseases, including Alzheimer's and multiple sclerosis.
However, this development has also raised widespread concerns about whether this technology will eventually lead to experiments in cloning babies in the laboratory, such as re-cloning a lost child by a parent who has lost a child. Although there have been precedents for cloning human embryos before, healthy human stem cells have not been successfully extracted from these cloned embryos. This breakthrough means that scientists are technologically a step further from the clone.
The team of American scientists doing this work emphasizes that their work is aimed at trying to find ways to overcome some of the incurable diseases that have not been cured before. However, there is widespread concern that their technology will be easily taken for cloning by some ill-intentioned mad scientists. Human research.
Dr. David King, founder of the American lobbying group "Human Gene Alert", called for an agreement on a global scale that would completely ban the development of clone technology. And he also said that the researchers published their detailed stem cell extraction technology program through papers as an "extremely irresponsible" behavior. The Oregon Health and Science University, which achieved this breakthrough, used a similar technique to the British scientists who cloned the lamb Dolly.
First, Dr. Shoukhrat Mitalipov received an egg donated by a healthy woman and then carefully removed its DNA components. He then carefully placed the human skin cells in the egg cells that had been hollowed out, and then used electrical stimulation to cause them to begin to develop into embryos. When the embryo grows to 5 to 6 days old, its size is comparable to the flat head of a tack. At this time Dr. Mitalipuf recovered these embryos for stem cell extraction. These cells can transform into any cell type in an adult, and are therefore expected to become a human patch in the future to produce and replace organs that are diseased or aged in the human body.
Dr. Mitalipuf has spent many years continually improving the technology, including even the practice of adding caffeine to the mother cells at critical points in time. He said: "Our progress suggests a new way to get stem cells, which will hopefully help people replace their damaged tissues or organs. Stem cells can replicate and replace those damaged cells and tissues that need replacement. To help millions of people relieve their pain. Although we still have a lot of work to do before we finally develop safe and effective stem cell therapy, we believe this progress is an important milestone towards stem cell therapy."
In the future, as long as the small size of the patient's skin is extracted, it can be ensured that the substitute product produced by stem cell technology is completely matched with the patient. This will greatly enhance the effectiveness of the treatment, and eliminate the painful process of the body's immune rejection due to the use of drugs to control organ transplants. The tailored stem cell therapy will also help reveal more details of the patient's condition and help. Drug developers test which drugs work best.
Chris Mason is a professor of regenerative medicine at University College London in the UK. He commented on the work of the Mitalipuf group published in the journal Cell. “It seems to be moving.†And the University of Edinburgh, UK Dr. Paul De Sousa said that further understanding of our understanding of human eggs will help in the treatment of infertility. However, some scientists are worried about this. They are very worried that this technology will be transferred to human cloning research.
In the UK, the law stipulates that cloned embryos must be destroyed after 14 days, and it is illegal to transplant cloned embryos into women. In other countries, restrictions on this so-called “reproductive cloning†are much more relaxed.
Josephine Quintavalle, a member of the lobbying group's “Reproductive Ethics Review,†questioned the need for this research because he believes that stem cells can be achieved using a simpler approach available. Extraction. She said: "I suspect that the purpose of this study is not stem cell therapy at all, because other methods have proven to be effective in this area. Let us hope that the purpose of this study will not deviate more and more from reproductive cloning. direction."
Dr. Mitalipuf said that his team had failed in trying to clone monkeys, so he did not think that their technology could be transferred to human cloning attempts. In addition, some scholars have pointed out that an embryo that has only grown for five or six days is far from the practice of cloning human beings. There is no inevitable connection between the two.
However, Dr. King warned: "This technology is the technology that mad scientists who have been hoping to clone people need, that is, the technology to reliably breed human embryos for cloning." He said: "So create a International agreements to completely ban more research in this area and prevent the cloning of human body becomes necessary. It is extremely irresponsible to publish this paper in this context."
In 2004, South Korean scientist Hwang Woo-suk claimed that his team had successfully completed the first human embryo cloning and successfully extracted stem cells from cloned embryos. However, it was later confirmed that his research had fraudulent behavior, and he himself was also accused of illegal misappropriation of funds and other charges. (morning wind)
Source: Sina Technology News
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